Chung Lab News

MAP technology featured in Tech Crunch
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MAP technology featured in Tech Crunch

This new brain-scanning technique is literally mind expanding

Sometimes it’s hard to tell the difference between science and technology ó almost all the time when it has to do with the brain. But this research from MIT that allows for vastly improved scans of the networks inside the brain is too cool to pass up, whether it’s tech, science, or somewhere in between.

Getting up close and personal with neurons and other brain cells is a science that people have been working on for a century and more. Mainly the problem is that they’re so darn small, and packed so tightly, and connect in so many places at once, that it’s hard to tell where anything’s going. We have ways of imaging the brain at various levels, but each is highly limited in its own way.

This new technique addresses several of the main problems. It’s called magnified analysis of proteome, or (conveniently) MAP. The summary from lead researcher Kwanghun Chung makes it sound almost too good to be true.

“We use a chemical process to make the whole brain size-adjustable, while preserving pretty much everything,” Chung says in an MIT news release. “We preserve the proteome (the collection of proteins found in a biological sample), we preserve nanoscopic details, and we also preserve brain-wide connectivity.”

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SWITCH paper published in Cell
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SWITCH paper published in Cell

The Chung Lab published a paper in Cell, introducing a simple method for multiple rounds of relabeling yielding multiplexed proteomic imaging.

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Kwanghun Chung awarded Packard Fellowship
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Kwanghun Chung awarded Packard Fellowship

The David and Lucile Packard Foundation named 18 of the nation’s most innovative early-career scientists and engineers as recipients of the 2015 Packard Fellowships for Science and Engineering. Each Fellow will receive a grant of $875,000 over five years to pursue their research.

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Prof. Kwanghun Chung Named to Cell 40 Under 40
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Prof. Kwanghun Chung Named to Cell 40 Under 40

To celebrate 40 years of Cell, we invited 40 scientists from around the world and working in diverse biological fields—all under the age of 40—to talk about science, their personal philosophies, the joys and challenges of research, and their lives away from the bench.

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